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hmgbiotech HM-120
HMGB 1是細(xì)胞核的一個(gè)組成部分，在基因組的組織和表達(dá)中具有多種功能。HMG生物技術(shù)SRL為活躍在這一領(lǐng)域的其他研究人員和公司提供試劑、服務(wù)和想法。它還有助于實(shí)驗(yàn)室開發(fā)分析和試劑。
hmgbiotech DISULFIDE HMGB1說(shuō)明書
hmgbiotech HM-120
HMGB1是一種核蛋白，其由壞死細(xì)胞被動(dòng)釋放，由凋亡細(xì)胞保留，并由炎癥細(xì)胞主動(dòng)分泌（Dumitriu等人，HMGB1:從內(nèi)部引導(dǎo)免疫。Trends Immunol 2005，26:381-7）。HMGB1對(duì)生命至關(guān)重要：HMGB1基因敲除小鼠出生后不久死亡。
HMGB1作為運(yùn)動(dòng)細(xì)胞的化學(xué)引誘劑和細(xì)胞因子的誘導(dǎo)劑的兩種不同活性被歸因于不同的生物化學(xué)形式。還原的HMGB1（具有化學(xué)引誘活性的形式）被還原；二硫化物HMGB1包含C23和C45之間的二硫鍵（完整注釋：HMGB1C23-C45C106h–Antoine J.等人（2014）。Mol-Med）。
二硫化物HMGB1可誘導(dǎo)單核細(xì)胞和其他炎癥細(xì)胞產(chǎn)生細(xì)胞因子和趨化因子（Venereau等人，2012）。
在結(jié)構(gòu)上，二硫化物HMGB1在半胱氨酸殘基23和45與還原的半胱氨酸殘基106之間具有二硫鍵。測(cè)試二硫化物HMGB1刺激細(xì)胞因子的能力
HMGBiotech公司熱銷產(chǎn)品
產(chǎn)品名稱 | 貨號(hào) |
100 ug Fully reduced HMGB1, LPS free | HM-115 |
50 ug Fully reduced HMGB1, LPS free | HM-116 |
100 ug Disulfide HMGB1, LPS free | HM-121 |
100 ug BoxA from HMGB1, LPS-free and tested in migration assay | HM-012 |
50 ug Disulfide HMGB1, LPS free | HM-122 |
500 ug BoxA from HMGB1, LPS-free and tested in migration assay | HM-013 |
1 mg HMGB1 for biochemistry | HM-100 |
2.5 mg BoxA from HMGB1, LPS-free and tested in migration assay | HM-014 |
250 ug HMGB1 biochemistry | HM-101 |
25 ug BoxA from HMGB1, LPS-free and tested in migration assay | HM-011 |
15 ug BoxB from HMGB1, LPS-free and tested in migration assay | HM-053 |
15 ug Fully reduced HMGB1, LPS free | HM-117 |
10 ug Disulfide HMGB1, LPS free | HM-123 |
15 ug Non-oxidizable HMGB1, LPS free | HM-133 |
250 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration | HM-170 |
100 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration | HM-171 |
50 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration | HM-172 |
15 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration | HM-173 |
50 ug HMGB1 15N labelled for Mass Spectrometry | HM-180 |
5 ug HMGB1 15N labelled for Mass Spectrometry | HM-181 |
2.5 mg BoxA 2D from HMGB1, LPS-free and tested in migration assay | HM-190 |
500 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay | HM-191 |
100 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay | HM-192 |
25 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay | HM-193 |
Control cell lysates from Hmgb1 +/+ | HM-001 |
Control cell lysates from Hmgb1 -/- | HM-002 |
1 mg BoxB from HMGB1, LPS-free and tested in migration assay | HM-050 |
250 ug BoxB from HMGB1, LPS-free and tested in migration assay | HM-051 |
100 ug BoxB from HMGB1, LPS-free and tested in migration assay | HM-052 |
500 ug Fully reduced HMGB1, LPS free | HM-114 |
250 ug Disulfide HMGB1, LPS free | HM-120 |
500 ug Non-oxidizable HMGB1, LPS free | HM-130 |
100 ug Non-oxidizable HMGB1, LPS free | HM-131 |
50 ug Non-oxidizable HMGB1, LPS free | HM-132 |
500 ug HMGB2, LPS-free and tested in migration assay | HM-151 |
100 ug HMGB2, LPS-free and tested in migration assay | HM-152 |
50 ug HMGB2, LPS-free and tested in migration assay | HM-153 |
Embryonic fibroblasts immortalized with large T antigen. One vial of -/- cells and one vial of +/+ cells | HM-201 |
Embryonic fibroblasts immortalized with the 3T3 method. One vial of -/- cells and one vial of +/+ cells | HM-221 |
Embryonic fibroblasts, Hmgb1-/- and HMGB2-low, immortalized with the 3T3 method. One vial of cells, and | HM-223 |
HMGB1 Isoforms Kit - Test size | HM-030 |
Embryonic fibroblasts immortalized with the 3T3 method. One vial of Hmgb2-/- cells and one vial of +/+ cells | HM-251 |
HMGB1 Isoforms Kit - Regular size | HM-031 |
20 ug p-mHMG1 | HM-300 |
50 ug Terminally oxidized HMGB1, LPS free | HM-062 |
20 ug p-mHMG1tag | HM-301 |
100 ug Terminally oxidized HMGB1, LPS free | HM-061 |
20 ug pEGFP-HMGB1 | HM-302 |
250 ug Terminally oxidized HMGB1, LPS free | HM-060 |
20 ug pcDNA/FL-RAGE plasmid | HM-310 |
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